Bai, D., et al. Impact of Side Chain Structure and Aglycon Carbonyl Group on the Immunostimulatory Activities of Semisynthetic Saponin Adjuvants. ACS Pharmacol Transl Sci, 2026 Feb 20, 9(3):706-715, PMID: 41852640

The saponin QS-21, derived from Quillaja saponaria, has been clinically successful in vaccines due to its ability to elicit robust humoral and cellular immunity, exemplified by its inclusion in [...]

Bundi, C.K., et al. B and T cell responses to pre-erythrocytic R21/Matrix-M and blood- stage RH5.1/Matrix-M malaria vaccines in endemic settings. Front Immunol, 2026 Mar 2, 17:1743327, PMID: 41846927

 Malaria remains a major global health challenge, particularly in endemic regions where effective vaccines are critically needed. Recent advances include the development of vaccines targeting [...]