Ma W. et. al.: Enhanced Antitumor Immunity of a Globo H-Based Vaccine Enabled by the Combination Adjuvants of 3D-MPL and QS-21.
The study presents a novel adjuvant-assisted Globo H-based anticancer vaccine platform. The article advocates for the efficacy of a combination QS-21/3D-MPL adjuvant.
Read More
Venkatraman, N., et al. Evaluation of a novel malaria anti-sporozoite vaccine candidate, R21 in Matrix-M adjuvant, in the UK and Burkina Faso: two phase 1, first-in-human trials.
Comments from Desert King: The R21/Matrix-M malaria vaccine uses Novavax's proprietary Matrix-M adjuvant technology to help prevent malaria in children. The R21 Ag was de...
Read More
Pirahmadi S. et. al.: Selection of combination adjuvants for enhanced immunogenicity of a recombinant CelTOS vaccine against Plasmodium falciparum.
In the current study, the immunogenicity of Plasmodium falciparum cell traversal protein for ookinetes and sporozoites (PfCelTOS) were intended to improve by three differ...
Read More
Luna, E., et al. SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate.
An innovative novel adjuvant system, SPA14, which combines the QS-21 saponin with a synthetic TLR4 agonist, E6020, in cholesterol-containing liposomes, has shown promisin...
Read More
Yousefpour, P., et al. Modulation of antigen delivery and lymph node activation in nonhuman primates by saponin adjuvant saponin/monophosphoryl lipid A nanoparticle.
This article emphasizes the significance of the saponin QS-21/monophosphoryl lipid A nanoparticles (SMNP) using an HIV Env trimer model Ag, in enhancing immune responses ...
Read More