Bundi, C.K., et al. B and T cell responses to pre-erythrocytic R21/Matrix-M and blood- stage RH5.1/Matrix-M malaria vaccines in endemic settings. Front Immunol, 2026 Mar 2, 17:1743327, PMID: 41846927
Malaria remains a major global health challenge, particularly in endemic regions where effective vaccines are critically needed. Recent advances include the development ...
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Devine, J., et al. Infection, vaccination and risk of dementia: a proposed immunological model. Front Immuno, 2026 Mar 4, 17:1748535, PMID: 41859113
This paper emphasizes the growing global burden of dementia, particularly Alzheimer's disease, which is predicted to nearly double by 2050 due to aging populatio...
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San Martín, R., et al. Structure and immunological activity of QS-21 variant from Quillaja saponaria aerial biomass. Front Immunol, 2026 Mar 9, 17:1771912, PMID: 41878432
This study focuses on QS-21, a potent saponin adjuvant essential for human vaccines, traditionally sourced from the bark of mature Quillaja saponaria trees in Chile. The...
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Osbourn, A. The Cinderella tree, Quillaja saponaria – A soap story. Plants People Planet. 2026 Mar, 8(2):439-451, PMID: 41743997
The Quillaja saponaria tree, native to central Chile, has historically been valued for its soap-like bark containing saponins, which produce foam and have traditional cl...
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Ji, Y., et al. Exploring the Impact of Adjuvants on Vaccine Immunity Through Hematopoietic Cells. Vaccines (Basel), 2026 Feb 5, 14(2):155. PMID: 41746076
The paper explores how various adjuvants influence the immune response and hematopoietic pathways, particularly focusing on megakaryocytes and platelets, which are emergi...
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Sengupta, A. and Bhattacharyya, J. Overcoming Challenges in Dengue Vaccine Development: Advanced Delivery Approaches. Mol Pharm, 2026 Feb 15, PMID: 41693158
This paper addresses the critical global health challenge posed by dengue virus, emphasizing the complexities in developing a safe, effective, and long-lasting vaccine ca...
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Bülow, F.E., et al. A novel thin layer chromatography based method for the quantification of quillaic acid saponins. J Pharm Biomed Anal, 2026 Jun 15, 273:117409. PMID: 41687224
This paper presents a novel, cost-effective thin-layer chromatography (TLC) -based method for quantifying quillaic acid saponins, key bioactive compounds with significant...
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Kallenberg, J., et al. Preparing for Tuberculosis Vaccine M72/AS01E Implementation: A Global Demand Forecast and Key Influential Factors. Infect Dis Ther, 2026 Feb 25, PMID: 41739348
This paper provides a comprehensive, data-driven forecast of global demand for the novel M72/AS01E tuberculosis vaccine, which has the potential to significantly reduce T...
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