Enzymology and Structural Basis of Glycosyltransferases Involved in Saponin C28 Carboxylic Acid O‑d‑Fucosylation
Hudson, G.A., et al. Enzymology and Structural Basis of Glycosyltransferases Involved in Saponin C28 Carboxylic Acid OdFucosylation. JACS Au, 2025 Nov 24, 5(12):6011- 602...
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QS-21: Structural insights, immunological mechanisms, and prospects for rational design of safer vaccine adjuvants
Hu, Y., et al. QS-21: Structural insights, immunological mechanisms, and prospects for rational design of safer vaccine adjuvants. Eur J Med Chem, 2026 Jan 5, 301:118223....
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TB vaccine development: monitoring international patent filings to anticipate access challenges
Pignataro, M.F., et al. TB vaccine development: monitoring international patent filings to anticipate access challenges. Front Public Health, 2026 Jan 16, 13:1726153. PMI...
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Immunogenicity of a Recombinant Zoster Vaccine (gE/BFA01) in Mice
Quan, Y., et al. Immunogenicity of a Recombinant Zoster Vaccine (gE/BFA01) in Mice. Viruses, 2025 Dec 30, 18(1):53. PMID: 41600818 This study addresses the signifi...
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Ferguson, M., et al. Immune persistence and safety of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein-based vaccine in adults 50-59 years of age, including at-increased-risk adults: A randomized controlled trial. Hum Vaccin Immunother, 2025 Dec, 21(1):2579335. PMID: 41194599
Respiratory syncytial virus (RSV) is a leading cause of respiratory illness across all age groups, particularly affecting infants, older adults, and individuals with chro...
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Rayens, E., et al. Adjuvanted Recombinant Zoster Vaccine is Effective Against Herpes Zoster Ophthalmicus, and is Associated With Lower Risk of Acute Myocardial Infarction and Stroke in Adults Aged ≥50 Years. Clin Infect Dis, 2025 Dec 24, 81(5):e441-e445. PMID: 40795767
Herpes zoster (shingles) and its complication, herpes zoster ophthalmicus (HZO), are associated with an increased risk of cardiovascular events such as heart attacks and ...
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Shrivastava, S., et al. ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates. NPJ Vaccines, 2025 Dec 19, PMID: 41419739
The development of an effective HIV-1 vaccine remains a global health priority due to the persistent high prevalence of HIV/AIDS despite advances in treatment and prevent...
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Talukdar, P., et al. From bark to bench: innovations in QS-21 adjuvant characterization and manufacturing. Front Immunol, 2025 Dec 2, 16:1677995. PMID: 41409277
This paper provides an overview of QS-21, a potent saponin-based adjuvant derived from the bark of Quillaja saponaria, highlighting its significant role in enhancing both...
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