Scientific Papers

This paper explores the application of CoPoP liposome-based nanotechnology, particularly focusing on the incorporation of saponins like QS-21 as adjuvants, to enhance vaccine efficacy in [...]

This paper is about another adjuvant formulation method with QS-21. This study presents a novel approach to improving the safety and efficacy of QS-21, a potent saponin adjuvant widely used in [...]

This paper describes the development of a vaccine controlling Staphylococcus aureus-induced mastitis in dairy cattle, using saponin-based adjuvants, NanoQuil, a third-generation immunostimulating [...]

This paper is significant for its innovative use of the saponin adjuvant QS-21 in a self-adjuvanting vaccine targeting melanoma. The authors designed a GM3-based conjugate vaccine that [...]

This review paper provides a comprehensive overview of recent advances in the heterologous biosynthesis of QS saponins, with a particular focus on QS-21. It highlights the significance of QS-21 [...]

This article presents a compelling case for the development of an Epstein–Barr virus (EBV) vaccine, emphasizing the potential role of saponin-based adjuvants such as Matrix-M in enhancing vaccine [...]

This phase III open-label study evaluates the immunogenicity and safety of co-administering two adjuvanted vaccines: the AS01E-adjuvanted RSV prefusion F protein vaccine (Arexvy) and the [...]

This study introduces a novel, versatile liquid chromatography method coupled with charged aerosol detection (LC-CAD) for the reliable quantification and stability monitoring of QS-21, widely [...]

This paper introduces a novel, structure-based prion vaccine that effectively targets the infectious form of the prion protein (PrP^Sc) by mimicking its disease-specific surface features, [...]

This paper, closely related to the previous one, presents a novel platform for developing recombinant influenza vaccines using adjuvanted nanoliposomes that incorporate saponin-based adjuvants, [...]