Scientific Papers

The study evaluated different vaccine formulations incorporating Leishmania amazonensis antigens (LaAg) combined with various adjuvants, including complete Freund’s adjuvant (CFA), saponin (SAP), [...]

The study evaluates the efficacy and safety of the R21 malaria vaccine candidate (Jenner Institute, University of Oxford) formulated with the Matrix-M adjuvant (Novavax) in a phase 1–2a malaria [...]

The use of an appropriate adjuvant is crucial for developing an effective HIV vaccine. This study investigates the efficacy of QS-21-based saponin/monophosphoryl lipid A nanoparticle (SMNP) and [...]

The article explores the promising role of phytochemicals, particularly saponins like Quil A and its derivative QS-21 from Quillaja saponaria, in enhancing cancer immunotherapy.

Bovine colostrum has the potential to serve as a source of neutralizing antibodies for preventing viral infections due to the evolutionary homology between bovine and human immunoglobulins.

The study evaluated the stability of two recombinant Cytomegalovirus antigens (gB and Pentamer) formulated with the SPA14 adjuvant system, a liposomal formulation containing QS-21 and the [...]

The paper presents several key findings regarding saponin-based adjuvants (SBAs), particularly focusing on their mechanism of action and efficacy in enhancing immune responses.

The study indicates that nano-adjuvants offer a promising alternative to traditional adjuvants for inducing robust and lasting immune responses, particularly in the context of developing vaccines [...]

The study presents a novel adjuvant-assisted Globo H-based anticancer vaccine platform. The article advocates for the efficacy of a combination QS-21/3D-MPL adjuvant.

Comments from Desert King: The R21/Matrix-M malaria vaccine uses Novavax's proprietary Matrix-M adjuvant technology to help prevent malaria in children. The R21 Ag was developed by the University [...]