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  • Home
  • About Us
  • Raw Materials
    • Quillaja Management
    • Yucca Management
    • Jojoba Management
  • Lines of Business
    • Pharmaceuticals
    • Animal Nutrition and Health
    • Food and Beverages
    • Personal Care and Cosmetics
    • Agriculture
    • Environment and Mining
  • Quality
  • News
  • Contact
  • English
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Photo Albums

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By Matias Bobadilla
In Uncategorized
Posted 26 October, 2026

Regional Pride: Desert King’s global leadership in quillaja extracts

At Desert King, we are proud to bring the best of Chilean nature to the global stage. Through SOFOFA’s “Orgullo Regional” (Regional Pride) campaign, we reaffirm our commitment to [...]

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 Wei, L., et al. Saponin derivative and MPLA-adjuvanted intranasal protein nanoparticle vaccines induce potent mucosal immunity and durable heterologous influenza protection in mice
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By Matias Bobadilla
In Scientific Papers
Posted 16 September, 2026

Wei, L., et al. Saponin derivative and MPLA-adjuvanted intranasal protein nanoparticle vaccines induce potent mucosal immunity and durable heterologous influenza protection in mice

Nanomedicine, 2026 Aug 19:103008. PMID: 42617671 The authors introduce a novel intranasal protein nanoparticle influenza vaccine formulated with a semisynthetic saponin derivative, VSA-2, [...]

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 Lu, J., et al. Lysosomal disruption elicits immunogenic cell death: A saponin-nanoaluminum adjuvant for enhanced cancer immunotherapy
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By Matias Bobadilla
In Scientific Papers
Posted 16 September, 2026

Lu, J., et al. Lysosomal disruption elicits immunogenic cell death: A saponin-nanoaluminum adjuvant for enhanced cancer immunotherapy

Acta Biomater, 2026 Aug, 220:276-291. PMID: 42468600 This paper introduces a novel saponin-based nanoadjuvant, QS-NanoAlum, that leverages lysosomal disruption to induce immunogenic cell death [...]

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 Eckhardt, E., et al. Comparison of the adjuvant effect of AS01, AS03 and alum on the immune response to GMP-grade H5N1 antigen in guinea pigs
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By Matias Bobadilla
In Scientific Papers
Posted 16 September, 2026

Eckhardt, E., et al. Comparison of the adjuvant effect of AS01, AS03 and alum on the immune response to GMP-grade H5N1 antigen in guinea pigs

Sci Rep, 2026 Aug 20, 16(1):26175. PMID: 42624960 Read this comprehensive comparison of the adjuvant effects of two advanced formulations, AS01 (containing QS-21 saponin and MPL-A) and AS03 (a [...]

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 Steichen, J.M., et al. Vaccination elicits HIV broadly neutralizing antibodies in primates
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By Matias Bobadilla
In Scientific Papers
Posted 16 September, 2026

Steichen, J.M., et al. Vaccination elicits HIV broadly neutralizing antibodies in primates

Nature, 2026 Aug, 656(8128):723-733. PMID: 42380658 Building upon the design of germline-targeted Env immunogens that effectively prime V2 apex bnAb precursors (see previous paper from Marchitto [...]

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 Marchitto, L., et al. Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies
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By Matias Bobadilla
In Scientific Papers
Posted 16 September, 2026

Marchitto, L., et al. Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

Nature, 2026 Aug, 656(8128):712-722. PMID: 42380659 This Nature paper presents a significant advance in HIV vaccine design by demonstrating that germline-targeted Env immunogens can rapidly prime [...]

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 Tregunno, C., et al.  AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine (Adjuvanted RSVPreF3): Review of the First 2 Years of Post-Marketing Safety Surveillance
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By Matias Bobadilla
In Scientific Papers
Posted 16 September, 2026

Tregunno, C., et al. AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine (Adjuvanted RSVPreF3): Review of the First 2 Years of Post-Marketing Safety Surveillance

Drug Saf, 2026 Aug 1. PMID: 42541670 Are you interested in a comprehensive two-year post-marketing safety surveillance of the AS01E-adjuvanted RSVPreF3 vaccine? This paper employs the liposomal [...]

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 Zhang, Y., et al. CD25+ cell depletion enhances protective immunity of PR8 inactivated influenza vaccine in aged mice. Virology, 2026 Aug, 621:110938. PMID: 42107283
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By Matias Bobadilla
In Scientific Papers
Posted 14 August, 2026

Zhang, Y., et al. CD25+ cell depletion enhances protective immunity of PR8 inactivated influenza vaccine in aged mice. Virology, 2026 Aug, 621:110938. PMID: 42107283

This paper highlights the synergistic potential of combining saponin-based ISCOM adjuvants with immune regulatory modulation, specifically transient depletion of CD25+ regulatory T cells, to [...]

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 Pyles, K., et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. NPJ Vaccines, 2026 Jul 10. PMID: 42431930
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By Matias Bobadilla
In Scientific Papers
Posted 14 August, 2026

Pyles, K., et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. NPJ Vaccines, 2026 Jul 10. PMID: 42431930

This study evaluates the immunogenicity and protective efficacy of a recombinant H5 hemagglutinin (HA) nanoparticle vaccine adjuvanted with Matrix-M, administered either intranasally or [...]

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 Haupt, S., et al.  Rapid boosting increases germinal center responses to sequential vaccines. Nat Immunol, 2026 Jul, 27(7):1476-1489. PMID: 42337116
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By Matias Bobadilla
In Scientific Papers
Posted 14 August, 2026

Haupt, S., et al. Rapid boosting increases germinal center responses to sequential vaccines. Nat Immunol, 2026 Jul, 27(7):1476-1489. PMID: 42337116

This paper explores how rapid boosting strategies can significantly enhance germinal center (GC) responses in the context of HIV vaccination, particularly emphasizing the role of saponin-based [...]

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