Márquez, P.G., et al. Cooperative supramolecular integration of QS-21 into polymeric micelles as a tunable nanoadjuvant platform for subunit vaccines. RSC Adv. 2026 May 1, 16(25):22897-22915. PMID: 42080164

This paper is about another adjuvant formulation method with QS-21. This study presents a novel approach to improving the safety and efficacy of QS-21, a potent saponin adjuvant widely used in [...]

Liang, R., et al. Ganglioside GM3 and Lipid A Mimetic Conjugate Combined with EcMPLA and QS-21 as a Potential Vaccine Candidate for Cutaneous Melanoma Immunotherapy. J Med Chem, 2026 May 14, 69(9):11434-11447. PMID: 42077094

This paper is significant for its innovative use of the saponin adjuvant QS-21 in a self-adjuvanting vaccine targeting melanoma. The authors designed a GM3-based conjugate vaccine that [...]