Publications

Abstract The cytotoxic mechanism of the saponin QS-21 and its aglycone quillaic acid (QA) was studied on human gastric cancer cells (SNU1 and KATO III). Both compounds showed in vitro cytotoxic [...]

Scientists are using Chilean quillaja extract to create nano-scale oleogels in plant-based proteins, mimicking the taste and texture of fat in meat and creating a ‘juicy’ product [...]

Can Çokçalışkan, Tunçer Türkoğlu, Beyhan Sareyyüpoğlu, Ergün Uzunlu, Ayca Babak, Banu B. Özbilge, Veli Gülyaz Foot-and-mouth disease (FMD) is one of the most important animal diseases in the [...]

Robyn Marty-Roix, Gregory I. Vladimer, Kimberly Pouliot, Dan Weng, Rachel Buglione-Corbett, Kim West,John D. MacMicking, Jonathan D. Chee, Shixia Wang, Shan Lu, and Egil Lien Many [...]

Identification of QS-21 as an inflammasome-activating molecular component of saponin adjuvants Robyn Marty-Roix, Gregory I. Vladimer, Kimberly Pouliot, Dan Weng, Rachel Buglione- Corbett†, Kim [...]

Differential immune responses to HIV-1 envelope protein induced by liposomal adjuvant formulations containing monophosphoryl lipid A with or without QS21 Zoltan Becka,Gary R. Matyas, Rashmi [...]

Daming Zhu1* and Wenbin Tuo2 QS-21 is one of the active fractions of the bark of Chilean tree, Quillaja saponaria, purified using a reverse-phase chromatography (RP-HPLC) [1-3]. QS denotes its [...]

Potent response of QS-21 as a vaccine adjuvant in the skin when delivered with the Nanopatch, resulted in adjuvant dose sparing. Hwee-Ing Ng, Germain J. P. Fernando, Alexandra C. I. Depelsenaire [...]

Fusce iaculis eros a purus tristique malesuada. Integer quis dui in elit blandit suscipit eget ut orci. Mauris egestas erat mauris, quis blandit sapien viverra ac. Mauris at orci porta diam [...]

Fusce iaculis eros a purus tristique malesuada. Integer quis dui in elit blandit suscipit eget ut orci. Mauris egestas erat mauris, quis blandit sapien viverra ac. Mauris at orci porta diam [...]