Scientific Papers

The use of an appropriate adjuvant is crucial for developing an effective HIV vaccine. This study investigates the efficacy of QS-21-based saponin/monophosphoryl lipid A nanoparticle (SMNP) and [...]

The article explores the promising role of phytochemicals, particularly saponins like Quil A and its derivative QS-21 from Quillaja saponaria, in enhancing cancer immunotherapy.

Bovine colostrum has the potential to serve as a source of neutralizing antibodies for preventing viral infections due to the evolutionary homology between bovine and human immunoglobulins.

The study evaluated the stability of two recombinant Cytomegalovirus antigens (gB and Pentamer) formulated with the SPA14 adjuvant system, a liposomal formulation containing QS-21 and the [...]

The study indicates that nano-adjuvants offer a promising alternative to traditional adjuvants for inducing robust and lasting immune responses, particularly in the context of developing vaccines [...]

The study presents a novel adjuvant-assisted Globo H-based anticancer vaccine platform. The article advocates for the efficacy of a combination QS-21/3D-MPL adjuvant.

Comments from Desert King: The R21/Matrix-M malaria vaccine uses Novavax's proprietary Matrix-M adjuvant technology to help prevent malaria in children. The R21 Ag was developed by the University [...]

In the current study, the immunogenicity of Plasmodium falciparum cell traversal protein for ookinetes and sporozoites (PfCelTOS) were intended to improve by three different adjuvants.

An innovative novel adjuvant system, SPA14, which combines the QS-21 saponin with a synthetic TLR4 agonist, E6020, in cholesterol-containing liposomes, has shown promising results in enhancing [...]

This article emphasizes the significance of the saponin QS-21/monophosphoryl lipid A nanoparticles (SMNP) using an HIV Env trimer model Ag, in enhancing immune responses to vaccines significantly [...]