This paper highlights the synergistic potential of combining saponin-based ISCOM adjuvants with immune regulatory modulation, specifically transient depletion of CD25+ re...

This study evaluates the immunogenicity and protective efficacy of a recombinant H5 hemagglutinin (HA) nanoparticle vaccine adjuvanted with Matrix-M, administered either ...

This paper explores how rapid boosting strategies can significantly enhance germinal center (GC) responses in the context of HIV vaccination, particularly emphasizing the...

This paper uniquely explores how the adjuvant AS01 enhances immune responses in aged populations, focusing on its role in overcoming immunosenescence. By comparing respon...

This paper presents the design and feasibility considerations for a phase 3 efficacy trial of the M72/AS01E-4 tuberculosis vaccine, which incorporates the AS01 adjuvant s...

This paper offers a comprehensive overview of next-generation vaccine adjuvants, with particular emphasis on nanotechnology, systems immunology, and computational approac...

This paper provides a comprehensive overview of advanced nanoparticle-based vaccine platforms, including a focused emphasis on saponin-derived self-assembling nanoplatfor...

This paper is a significant contribution to the field of saponin-based adjuvants, particularly highlighting the potent immunostimulatory capacity of the saponin-MPLA nano...